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5.0L (1979-1995) MustangTechnical discussions on 5.0 Liter Mustangs within. This does not include the 5.0 from the 2011 Mustang GT. That information is in the 2005-1011 section.
Break in is a myth. It's a good idea to take it easy for a little bit to make sure that everything is how it should be, but there is no "break in" period
My Richmond gear set recomended a "break-in" but it was little more than driving continuously for 30 minutes, then letting the diff cool back down to ambient temperature, to work harden the gears. I dunno if that counts as "break-in" though. 30 miles later and the next day I was all over that thing, no problems