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I have a 2010 V6 also, and I have a JLT CAI and an AM Tune. Also run my car on the 93 race tune. Huge difference, don't know if you have an automatic, but it brings the transmission to life.
If this is going to be your first mod, go for it. Its the best thing to start with.
Ditto. And an upgraded throttle body is only needed for F/I set ups. Believe us, you're mustang is not even close to fighting for air with the stock throttle body.