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Make your own block. No small block, and I doubt any big blocks, can accomodate a 4.5" bore. But, that's not the question. The question is which would YOU design.
A 4.0 bore would be great on a modular!
A Big Bore from VT or Modular Performance is only 3.7 and thats about the max our blocks can go so i'd like to see the next generation have atleast a 4.0 bore.
Depends on the stroke. Each of those combos are similar in final cubes, even though each will act differently. The top two combos are real engines (289, slightly destroked and 4.6L), the other two aren't.
Larger bores = larger valve area = more air flow = more power
Short strokes = less low rpm torque = more high rpm power