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Asking if you can spray is not the right question, what you should be asking is "Will I hook up?"
You can always spray even with 4.56 gears.
he is absolutely right your problem is will you have traction.... whats your suspension, tires? you are capable of spraying on 4.10's, what shot are you planning on running?
I am spraying a 100 shot with my auto with 4;10's running 315/35 drag radials with no traction issues. the 275 street nittos did not do very well for me spraying out of the hole