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Pretty sure you'll need spacers. I see them all the time on craigslist, but I don't want to run spacers so I haven't bought any. Others will chime in if I'm wrong.
Do a search. There are a couple threads. I think for the 05+ stangs its a 1.5" spacer which is kinda iffy. I was about to do some 03 bullitts on my 54 with a 1" spacer which I dont want to mess with.
I tried putting the `05 v6 wheels on my 67 but yes, you need spacers. The front will need a 1.5" to clear the upper ball joint. The rear doesn't need spacers, but it might look alittle wierd having the front 3" wider than the rear.