Anybody know if the newer 2005+ mustang fly by wire thorttle body will fit and or work on an older 4.6 2 valve??

 

No it won't. The new 05+ is a twin bore throttle body and the earlier 4.6L 2v's were single bore.
Although. The 4.6's come in 70 and 75mm sizes and the 05+ V6's are also single bore, 70mm, and drive by wire. You would come alot closer to mounting and using the V6 one. Now you just have to figure out how to control it.

 

Why would you want to do this?

 

I have a 1978 F100 and I'm thinking of dropping in a new 4.6 or 5.4, I'm a disabled vet and an amputee right leg, with the fly by wire TB I can just move the gas pedal to the left and I don't need handicap controls then. I have a 2007 GT/CS and I moved the gas pedal over soddered in some extra wire for clearance and boom I have a factory looking setup for me to drive the car.

 

That's a very clever solution to your needs. Almost makes you think Ford should offer a simple kit for that to assist those with amputations or right side mobility issues.

 

The issue is going to be that the ECM controls the throttle. There's no extra or separate computer for that AFAIK. Best bet to do this would be to get a complete drive-by-wire engine with harness/ECM and put that into the F100.... or on a non-DBW setup, just run the throttle cable to the left-side by making a new hole in the firewall?

 

The cable idea has been hassed through also I need to find a 84-86 mustang 4 barrel carb plate to route the cable, but I like the idea of putting in a modern engine that get more power and better mileage, while also being lighter on the front end!!